In-silico Evaluation of Mirror Repeats in Some Selected Genes of Candida albicans

Sehrawat, Barkha and Yadav, Priya and Sarjeet, Mustak and Yadav, Sakshi and Yadav, Vidhi and Goyal, Nupur and Alam, Parvej and Ahlawat, Meghali and Yadav, Sandeep (2024) In-silico Evaluation of Mirror Repeats in Some Selected Genes of Candida albicans. Journal of Biology and Nature, 16 (1). pp. 39-52. ISSN 2395-5384

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Abstract

All cellular processes in a living cell are controlled by its genetic material. DNA in majority of the domains acts as a regulatory molecule by controlling various vital functions. The genetic makeup of DNA or RNA (in viruses) is unique in all the domains. Their uniqueness is determined by the presence of various types of repetitive patterns of bases. These includes inverted repeats, tandem repeats, VNTR’s, palindromes etc. Among many repetitive pattern types, Mirror repeats (MR) found to be dispersed throughout the genes or genomes. These sequences are associated with various functional features like their involvement in H-DNA formation, in replication & transcription, nervous system related diseases development etc. The major focus of this investigation is to identify MR sequences from some selected genes of Candida albicans using a bioinformatics based pipeline. The approach refers to as FPCB which utilized some manual steps to extract out MR sequence from any targeted gene or genome. The current study find out that the identified Mirror repeats found to be dispersed throughout the selected genes along with variable length. Among them the maximum & minimum MR sequences were reported in the gene FAS2 (108) & HIS1 (15) respectively. The present study will be helpful to provide a new insight for molecular as well as computational based studies of Candida albicans as well as other related fungal groups.

Item Type: Article
Subjects: Euro Archives > Biological Science
Depositing User: Managing Editor
Date Deposited: 13 Apr 2024 09:26
Last Modified: 13 Apr 2024 09:26
URI: http://publish7promo.com/id/eprint/4649

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