In silico ANALYSIS OF EFFECT OF PHYTOCHEMICALS FROM Paprika oleoresin (Capsicum annum L.) AGAINST DIAMINOPIMELATE DEHYDROGENASE OF Clostridium tetani CAUSING TETANUS

BEHERA, NABAKRUSHNA and SAHOO, ASHOK KUMAR and PANIGRAHI, GAGAN KUMAR and MISHRA, SARTHAK SIDDHANT and PATRA, SASMITA and PRAKASH, K. V. D. and BHATTACHARYAY, DIPANKAR (2020) In silico ANALYSIS OF EFFECT OF PHYTOCHEMICALS FROM Paprika oleoresin (Capsicum annum L.) AGAINST DIAMINOPIMELATE DEHYDROGENASE OF Clostridium tetani CAUSING TETANUS. PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY, 21 (19-20). pp. 53-55.

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Abstract

Clostridium tetani causes tetanus. Strikingly, tetanus rises primarily during specific molecular events, thus acting as a potential clinical biomarker. Further, tetanus may also activate further downstream events, supporting the detrimental phase. To restrict the activity of tetanus, several bio molecules can be deployed, of which the phytochemicals can be the best alternative. Molecular docking-based screening of a few phytochemicals revealed that the phytochemicals effectively associate with the active site of the protein and hence bears diagnostic and therapeutic potentials against tetanus.

Item Type: Article
Subjects: Euro Archives > Biological Science
Depositing User: Managing Editor
Date Deposited: 02 Dec 2023 04:16
Last Modified: 02 Dec 2023 04:16
URI: http://publish7promo.com/id/eprint/4131

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