BEE PROPOLIS USE IN BIOTIC AND ABIOTIC COMPOSITIONS AND ITS BIOLOGICAL ORIGIN FOR ANTICANCER MEDICINES

Propolis is a resinous compound with a balsamic aroma and a sticky consistency that is harvested from the exudates, flowers, and buds of several plants. These biological effects are tied to the phenolic chemicals found in propolis, the structure and concentration of which change depending on the region of production, the variety of plant resins available, the genetic makeup of the queen bee, the technique of production, and the time of year. Biomolecules isolated from plants have the potential to serve as the basis for anticancer medication prototypes with the ability to suppress tumour growth. The structure and concentration of propolis' phenolic compounds vary on the place of production, the range of plant resins accessible, the queen bee's genetic makeup, the manufacturing method, and the season. Plant biomolecules may be used to develop anticancer drugs that inhibit tumour growth. Tropical and subtropical regions are good for bioprospecting due of their biodiversity. Learning about these chemicals' efficacy is crucial since they could be utilised as adjuvants with other drugs or as new cancer treatments. Bee propolis is an important anticancer medication, but more preclinical and clinical research is needed to determine its selectivity, efficacy, and safety. We emphasised on the importance of bee propolis as an anticancer drug and focusing on the chemical components and biological processes.