MEDICINAL PLANTS FOR THE TREATMENT OF ALZHEIMER’S DISEASE: CURRENT TREATMENT & FUTURE PERSPECTIVE

Alzheimer's disease (AD) is a disorder of brain which progressively weakens the cognitive function. It is occur due to formation of β amyloid plaques & neurofibrillary tangles, & cholinergic neurotransmitter degeneration. At present there is no cure for this disease but currently it can be controlled by using a drugs which symptomatically treat the AD involve N-methyl D-aspartate (NMDA) receptor antagonist (memantine) & Acetylcholinesterase inhibitors (AChEIs) (donepezil, rivastigmine, galantamine). Natural treatment comprising various medicinal plants & herbs are utilize to treat brain disorders like dementia, amnesia, and AD from ancient time. Preclinical & clinical studies both are confirmed the therapeutic potential of herbal product for inhibition of AD. Medicinal plants shown effectiveness against Alzheimer’s probably because of their pleiotropic & multiple action which involves antioxidants, anti-inflammatory & neuroprotective activity. In this present review we focuses on the therapeutic potential of various medicinal plants which significantly contributed for treating AD & memory deficits.