Kalaa, Pruthu and Ramachandrana, Dittakavi (2020) Design, Synthesis and Biological Evaluation of Substituted StyrylIncorporated Quinazoline Derivatives as Anticancer Agents. In: Current Perspectives on Chemical Sciences Vol. 3. B P International, pp. 106-115. ISBN 978-93-90431-81-6
Full text not available from this repository.Abstract
A novel series of substituted aryl ethynyl incorporated quinazolines (11a-j) were designed and
synthesized, and their structures were characterized by 1HNMR, 13CNMR and mass spectral analysis.
Further, these compounds were screened for their preliminary anticancer activity against human
cancer cell lines like MCF-7 (human breast cancer), A549 (human lung cancer), DU-145 (human
prostate cancer) and MDA MB-231 (human breast cancer). Among all compounds, four compounds
(11b, 11c, 11d and 11g) were showed more potent activity than etoposide.
| Item Type: | Book Section |
|---|---|
| Subjects: | Euro Archives > Chemical Science |
| Depositing User: | Managing Editor |
| Date Deposited: | 15 Nov 2023 06:56 |
| Last Modified: | 15 Nov 2023 06:56 |
| URI: | http://publish7promo.com/id/eprint/3969 |
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