A Scientific Study: Analysis of Brain-Neuromuscular Synchronization and Coupling Strength in Muscular Dystrophy after NPT Treatment

Conte, Elio and Ware, Ken and Marvulli, Riccardo and Ianieri, Giancarlo and Megna, Marisa and Conte, Sergio and Mendolicchio, Leonardo and Pierangeli, Enrico (2020) A Scientific Study: Analysis of Brain-Neuromuscular Synchronization and Coupling Strength in Muscular Dystrophy after NPT Treatment. In: Current Topics in Medicine and Medical Research Vol. 2. B P International, pp. 57-78. ISBN 978-93-90206-18-6

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Abstract

We perform an analysis of brain-neuromuscular synchronization and coupling strength in muscular
dystrophy before and after NPT treatment. In order to estimate with accuracy the level of brain
synchronization, we introduce and use the method of the cross GMI that was elaborated by Pompe.
The finality is to account for the nonlinear chaotic dynamic contributions that regulate the dynamics.
We find that this method is excellent and it may be applied in such case of sEMG and EEG study as
well as at a general neurological level. By it we arrive to quantify the coupling strength and
synchronization first between two muscular sections (left and right trapezes) and after between Brain
activity, as recorded by the EEG, and the trapezes. We compare the results before and after the NPT
treatment and we find that the improvement obtained following such treatment is very consistent. We
have now in progress other studies relating in particular the application of such new methodologies to
other more serious pathologies as the HSP (Hereditary Spastic Paraplegia).

Item Type: Book Section
Subjects: Euro Archives > Medical Science
Depositing User: Managing Editor
Date Deposited: 27 Nov 2023 03:28
Last Modified: 27 Nov 2023 03:28
URI: http://publish7promo.com/id/eprint/3800

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