ENZYMATIC STUDY ON PATIENTS SUFFERING FROM ALCOHOLIC LIVER DISEASE (ALD) FROM PUNJAB (INDIA)

Enzymes have an emence diagnostic value for variety of disorders. In this study two of the transaminases i.e., serum glutamic oxaloacetic (S-GOT) and serum glutamic pyruvic transaminase (S-GPT) and alkaline phosphatase (ALP) have been included to asertain their relationship with type, quantity and duration of alcohol consumed in the patients suffering from alcholic liver disease (ALD) All the enzymes studied were found to be significantly higher in concentration when compared to the control group. S-GOT and S-GPT were raised maximally in the patients with alcoholic hepatitis (AH), while the increase in ALP concentration followed the progressive increase in Severity of ALD. Concentration of all enzymes was raised to its maximum level in the cases consuming home distilled liquor regularly, while the rise in values for S-GPT and ALP was low in individuals using English (IMFL) liquor in excess, the differences in concentration however, being insignificant.