Cytochrome C Oxidase 1 Divergences among Indian and Global Mosquito Species

Molecular phylogenetics elucidates the links between organisms. It uses a combination of molecular and statistical tools to create evolutionary links between live creatures or genes. Genetic distance is the number of mutation/evolutionary events between species since their divergence. The simplest way to calculate it is to count the number of difference between two sequences.Genetic distance is useful for reconstructing the history of populations. The primary goal of molecular phylogenetic research is to reconstruct the sequence of transformational events and represent them in developmental trees that graphically depict links between species or genes throughout time.At a time, distance analysis compares two aligned sequences and creates a matrix of all possible sequence pairs. The number of modifications (base substitutions and insertion/deletion events) are counted and given as a percentage of the overall sequence length for each comparison.Pairwise distances are final estimates of the difference between all possible pairs of sequences. Mosquito vectors are considered to be among the deadliest animals in the world. It is estimated that millions of people succumb to disease transmitted to humans by mosquitoes (WHO 2020).Changing climates have enabled invasive mosquito species previously confined to the tropics and subtropics to advance poleward and establish mosquito populations that have the potential to transmit pathogens that can cause disease.