Kinetic Behavior of Enzymes Immobilized Membranes in Potentiometric Biosensor: Homotopy Perturbation Method

Saranya, Jeganathan and Rajendran, Lakshmanan and Maheswari, Mariappan Uma (2022) Kinetic Behavior of Enzymes Immobilized Membranes in Potentiometric Biosensor: Homotopy Perturbation Method. In: Current Topics on Chemistry and Biochemistry Vol. 6. B P International (a part of SCIENCEDOMAIN International), pp. 1-24. ISBN 978-93-5547-942-6

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Abstract

Organophosphorus Hydrolase (OPH) immobilized in a pH-based potentiometric biosensor exhibits non-steady-state behaviour, according to a theoretical model that has been discussed. The model represents the concentration of substrate and hydrolysis products within the membrane and is based on a system of five coupled nonlinear reaction-diffusion equations for enzyme reactions occurring in potentiometric biosensors under non-steady-state conditions.With the help of a novel application of the homotopy perturbation method, new approximate analytical expressions for the substrate concentration (organophosphorus pesticides, or OPs) and products are obtained for all values of the Thiele modulus and buffer concentration. A good agreement is found when the analytical and numerical results are compared. The results apply to the entire solution domain.

Item Type: Book Section
Subjects: Euro Archives > Chemical Science
Depositing User: Managing Editor
Date Deposited: 09 Oct 2023 05:22
Last Modified: 09 Oct 2023 05:22
URI: http://publish7promo.com/id/eprint/3289

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