The Relationship between Homocysteine ​​and Fragility Fractures - A Systematic Review

It is known that increased levels of homocysteine in plasma ​​have been associated with various diseases. Current studies show that homocysteine ​​is a new risk factor for the development of osteoporosis. Fragility fractures are associated with increased morbidity, mortality and cause substantial financial loss to the patients and their families.

This mini-review provides a critical overview of currently available studies, examining the relationship between plasma homocysteine levels and fragility fractures. In conclusion more studies are needed to establish a clear relationship between homocysteine and fractures in elderly patients.