Predictors of outcome in patients with spontaneous intracereberal hemorrhage admitted to Liaquat University Hospital

Objective: To study the frequency of mortality and evaluate the influence of various prognostic factors such as Glasgow Coma Scale (GCS) Score, volume of hematoma and age on the outcome of the patient admitted with intracereberal hemorrhage. Methodology: This descriptive case series study was conducted at Liaquat University of Medical &Health Sciences hospital from July 2006 to March 2008. It included 399 consecutive patients with a diagnosis of SICH within 24 hours of their first stroke onset. Patients excluded from study were with hemorrhage secondary to brain tumors, to trauma, to hemorrhagic transformation of cerebral infarct and with previous history of hemorrhagic stroke. The patients’ data was collected in a well designed Proforma. The volume of hematoma was calculated according to ABC/2 formula. Quantitative variables were described as mean with±SD. While qualitative variables were described as frequency and percentages. Age, GCS score and volume of hematoma compared to the outcome of the patients by receiver operating characteristics (ROC). The level of Significance was <0.05. Results: This study included 399 patients of which 261(65.4%) were male and 138(34.6%) were female. The number of patients <65 years were 222 (55.6) whereas 177 (44.4%) patients were >65 years old. The number of patients who died during hospitalization were 122(30.6%) and 277 (69.4%) patients remained alive. AUR comparing the volume of hematoma is 0.707(p=0.001), GCS on admission 0.815(p=0.001) and age had 0.552 (p=095). Conclusion: This study showed elderly patients with decreased level of consciousness and hemorrhage > 60 ml have the worst outcome.