Highly Sensitive C Reactive Protein as a Predictor of in Hospital Outcome in Patients with Acute Coronary Syndrome

Background: C-reactive (CRP) protein is a well-studied inflammatory factor whose prognostic value in cardiovascular diseases in recent years has become increasingly important. Assesses of prognostic value of highly sensitive C-reactive protein (hs-CRP) in patients with acute coronary syndrome (ACS) wasthe aim of this work.

Methods: This observational research was conducted on 50 individuals had ACS admitted to CCU and indicated for invasive coronary angiography. Cases were classified in 2 groups depending on the level of hs-CRP: group A included (14) cases with hs-CRP > (2) and group B involved (36) cases with hs-CRP ≥ (2). All patients were subjected to: laboratory investigations (creatinine, urea, aspartate aminotransferase (AST), alanine amino transferase (ALT), troponin, creatine kinase myocardial band (CKMB), hs-CRP, HbA1C, lipid profile, twelve lead surface ECG, echocardiography and coronary angiography.

Results: Total cholesterol, LDL, HDL and triglyceride were significantly higher in group B compared to group A(P=0.001). Stent implantation was significantly higher in group 2 compared to group 1 (P=0.040)

Conclusions: There were correlation between hs CRP and lipid profile as a risk factor and there was no correlation between in hospital outcome and hs CRP in ACS patients due to small sized study.